MCH-102: ORGANIC CHEMISTRY-I Syllabus M.Sc. (CHEMISTRY) -1st-I Sem. Syllabus for DAVV Indore Affiliated Institutions

DEVI AHILYA VISHWAVIDYALAYA, DAVV INDORE Syllabus

M.Sc. (CHEMISTRY) First-1st-I Semester Curriculum/ Syllabus

 MCH-102: ORGANIC CHEMISTRY-I Syllabus

Unit-I

Chirality, Absolute and relative configuration, The terms chiral, achiral, stereogenic center (stereocenter), representations of three dimensional molecules, stereoisomerism resulting from
more than one stereogenic unit, Pi-diastereoisomerism and torsional chirality in carbon-carbon double bonds, some stereochemical reactions near a stereocenter (formation of diastereomers) stereoselective and stereospecific reactions, stereoisomerism in compounds without a stereogenic carbon, optical activity due to stereoplane (planar chirality)- paracyclophanes and transcyclooctene, optical activity of compounds due to helicity, asymmetric synthesis

Unit-II

Aromaticity, NMR spectroscopy and aromaticity, aromatic compounds, antiaromatic compounds, nonaromatic compounds, annulenes, ions, metallocenes Crown ether complexes and cryptates, phase transfer catalysis The Hammett equation- linear free energy relationship, Taft equation, steric effects, strain and Bredt rule

Unit-III

Aliphatic nucleophilic substitution, SN2 reaction as a stereospecific reaction, SN1 Mechanism-
Ion Pairs and other aspects, SNi and SET mechanisms, neighbouring group participationanchimeric assistance, non-classical carbocations Conformations and stereoisomerism of acyclic and cyclic systems, conformation and chemical reactivity

Unit-IV

Stereochemistry of elimination reactions, E1, E2 and E1cB mechanisms, elimination versus substitution Free radical reactions, Structure, stability and geometry, properties of free radicals

Books Suggested

1. J. March., Advanced Organic Chemistry: Reactions, Mechanisms and Structure, John Wiley
2. P. S. Kalsi. Stereochemistry, Conformation and Mechanism, New Age International
3. Peter Sykes, A guide book to mechanism in Organic chemistry, Orient-Longmans
4. E. L. Eliel, Stereochemistry of Carbon Compounds, McGraw-Hill
5. S. M. Mukherji and S. P. Singh, Reaction Mechanism in Organic Chemistry, Macmillan
6. F. A. Carey and R. J Sundberg, Advanced Organic Chemistry, Part A and B, Plenum
7. P. S. Kalsi., Organic Reactions and their Mechanisms, New Age International