MCH-105 (b) BIOLOGY FOR CHEMISTS Syllabus M.Sc. (CHEMISTRY) -1st-I Sem. Syllabus for DAVV Indore Affiliated Institutions

DEVI AHILYA VISHWAVIDYALAYA, DAVV INDORE Syllabus

M.Sc. (CHEMISTRY) First-1st-I Semester Curriculum/ Syllabus

 MCH-105 (b) BIOLOGY FOR CHEMISTS Syllabus
(For students without Biology in B.Sc.)

Unit-I: Cell structure and functions

Structure of prokaryotic and eukaryotic cells, intercellular organelles and their function comparison of plant and animal cells. Overview of metabolic processes -catabolism and  anabolism. ATP – the biological energy currency. Origin of life –unique properties of carbon.
Chemical evolution and rise of living systems.

Unit-II : Carbohydrates

Structure and function of important derivatives of monosaccharides like glycosides deoxy sugers, myoinositol, amino sugers. N-acetylmuramic acid. Sialic acid. Structural polysaccharide: Cellulose and chitin, Storage polysaccharide: Starch and glycogen. Structural and biological functions of glucosaminoglycans or mucopolysaccharides. Carbohydrates of glycoprotein and glycolipids. Role of sugars in biological recognition. Carbohydrate metabolism-Kreb’s cycle, glycolysis, glycogenesis and glycogenolysis, gluconeogenosis, pentose phosphate pathway.

Unit-III: Lipids

Fatty acids, essential fatty acids, structure and function of triacylglycerols,  glycerophospholipids, sphingolipids, Lippoproteins: Composition and function, role in atherosclerosis. Properties of lipids aggregates-micelles, bilayers, liposomes and their possible biological functions. Lipid metabolism-Beta-oxidation of fatty acids.

Unit-IV : Amino acids, Proteins and nucleic acid

Chemical and enzymatic hydrolysis of proteins to peptides, amino acid sequencing. Secondary
structure of proteins, α-helix ,-sheets. Super secondary structure, triple helix structure of collagen. Tertiary structure of protein-folding and domain structure. Quaternary structure. Amino acid metabolism-degradation and biosynthesis of amino acids, sequence  determination: chemical/enzymetic/mass spectral, recemization/detection. Chemistry of oxytocin and trytophan releasing hormone (TRH).
Chemical and enzymatic hydrolysis of nucleic acids. Structure of ribonucleic acids (RNA) and
deoxyribonucleic acids (DNA) double helix model of DNA and forces responsible for holding it. The chemical basis for heredity, an overview of replication of DNA, transcription, translation and genetic code. Chemical synthesis of mono and trinucleoside.

Books suggested:

1. Principles of Biochemistry, A.L. Lehninger, Worth Publishers.
2. Biochemistry, L. Stryer, W.H. Freeman.
3. Biochemistry, J.David Rwan, Nell Patterson.
4. Outlines of Biochemistry, E.E. Conn and P.K. Sumpf, John Wiley.