DEVI AHILYA VISHWAVIDYALAYA, DAVV INDORE Syllabus
M.Sc. (APPLIED CHEMISTRY) Fourth-3th-III Semester Curriculum/ Syllabus
MAP-304: Bioinorganic Chemistry Syllabus
Unit I Electron Transfer in Biology
Structure and function of metal of proteins in electron transport processes cytochrome's and ionsulphure proteins, synthetic models. Biological nitrogen fixation, and its mechanism, nitrogenase, Chemical nitrogen fixation.
Unit II Metalloporphyrins
Structure and optical spectra; heme proteins: magnetic susceptibility, epr and electronic spectra; hemoglobin and myoglobin: molecular structures, thermodynamics and kinetics of oxygenation, electronic and spatial structures, synthetic oxygen carriers, model systems; iron enzymes, peroxidase, catalase and cytochrome P-450
Unit III Metalloenzymes
Copper enzymes, superoxide dismutase, cytochrome oxidase and ceruloplasmin; Coenzymes; Molybdenum enzyme: xanthine oxidase; Zinc enzymes: carbonic anhydrase, carboxy peptidase and interchangeability of zinc and cobalt in enzymes; Vitamin B12 and B12 coenzymes; Iron storage, transport, biomineralization and siderophores, ferritin and transferrins..
Unit IV Metal Ions in Biological Systems
Bulk and trace metals with special reference to Na, K, Mg, Ca, Fe, Cu, Zn, Co, and K+/Na+ pump.
Text Books
1. S. J. Lippard & J. M. Berg. Principles of Bioorganic Chemistry, Panima Publ. Corpn. (2005).
2. E.-I. Ochiai. Bioinorganic Chemistry – An Introduction, Allyn and Bacon Inc. (1977).
3. M. N. Hughes. The Inorganic Chemistry of Biological Processes, Wiley (1981).
4. R.P. Hanzlik. Inorganic Aspects of Biological and Organic Chemistry, Academic Press (1976)
2. E.-I. Ochiai. Bioinorganic Chemistry – An Introduction, Allyn and Bacon Inc. (1977).
3. M. N. Hughes. The Inorganic Chemistry of Biological Processes, Wiley (1981).
4. R.P. Hanzlik. Inorganic Aspects of Biological and Organic Chemistry, Academic Press (1976)
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