MCH-203: PHYSICAL CHEMISTRY Syllabus MSc CHEMISTRY 2nd- II SemesterSyllabus for DAVV Indore Affiliated Institutions

DEVI AHILYA VISHWAVIDYALAYA, DAVV INDORE Syllabus

M.Sc. (CHEMISTRY) Second-2nd- II Semester Curriculum/ Syllabus

MCH-203: PHYSICAL CHEMISTRY-II Syllabus

Unit-I : Chemical Dynamics

Chemical kinetics: Empirical rate laws, Arrhenius equation, theories of reaction rates, determination of reaction mechanisms.

Kinetics of inorganic mechanisms : Hydrogen- Bromine reaction, Hydrogen- Chlorine Reaction. Decomposition of nitrogen pentaoxide, Decomposition of Ozone.

Kinetics of organic Decompositions : Pyrolysis of acetaldehyde, decomposition of ethane.

Unit-II : Surface Chemistry and Catalysis

Adsorption :Gibbs adsorption isotherm, BET equation and estimation of surface area .

Micelles:Surface active agents, classification of surface active agents, micellization, critical micellar concentration (CMC), factors affecting the CMC of surfactants, thermodynamics of micellization

Concepts of catalysis: Homogenous catalysis, kinetics of enzyme reactions,

Unit –III : Complex and Fast Reaction

Complex Reactions: Opposing reactions, Complex reactions, Parallel reactions , kinetics of free radical polymerization

Fast reactions: Experimental techniques for fast reactions viz., flow method, relaxation method, flash photolysis

Unit-IV: Applied Electrochemistry

Electrochemistry: Nernst equation, electrode kinetics, electrical double layer, Debye-Hückel theory. Voltammetry, Current voltage relationship, characteristics of DME, half-wave potential. Amperometric titrations.

Corrosion: Introduction to corrosion, forms of corrosion, Corrosion monitoring and prevention methods

Books Suggested

1. P.W. Atkins , Physical Chemistry, ELBS.

2. A.K. Chandra, Introduction to Quantum Chemistyry, Tata Mc Graw Hill.

3. Ira N. Levine, Quantum Chemistry, Prentice Hall.

4. K.J. Laidler, Chemical Kinetics. McGraw-Hill.

5. V. Moraoi, Micelles, Theoretical and Applied Aspects, Plenum.

6. A. J. Bard and L. R. Faulkner, Electrochemical Methods: Fundamentals and Applications, John Wiley & Sons: New York.

MCH-202: ORGANIC CHEMISTRY-II Syllabus M.Sc.(CHEMISTRY) 2nd-II Sem Syllabus for DAVV Indore Affiliated Institutions

DEVI AHILYA VISHWAVIDYALAYA, DAVV INDORE Syllabus

M.Sc. (CHEMISTRY) Second-2nd- II Semester Curriculum/ Syllabus

MCH-202: ORGANIC CHEMISTRY-II Syllabus

Unit-I

Common organic reactions and their mechanisms, base catalysed reactions, Stork Enamine  reaction, acid catalysed reactions, reactions of carboxylic acids and their derivatives Reagents in organic synthesis and relevant name reactions, organotransition metal reagents, some transition metal organometallic reactions, phosphorus containing reagents, organosulphur compounds, silicon reagents, boron containing reagents

Unit-II

Eletrophilic aromatic substitution- the arenium ion mechanism, orientation and reactivity, Ipso substitution, aromatic rearrangements Aromatic nucleophilic substitution-SNAr mechanism, SN1 mechanism, benzyne mechanism

Unit-III

Stereochemistry and mechanism of addition to carbon-carbon multiple bonds, addition reactions of alkenes and alkynes involving electrophiles, Birch reduction, epoxidation of alkenes Addition to carbon-hetero multiple bonds, addition to carbonyl compounds, metal hydride reduction, Meerwein-Ponndorf-Verley reduction, Wittig reaction

Unit-IV

Pericyclic reactions, conservation of molecular orbital symmetry, electrocyclic reactions, cycloaddition, sigmatropic rearrangements, the ene reaction, Mobius – Huckel analysis (PMO approach), correlation diagram method

Books Suggested

1. J. March., Advanced Organic Chemistry: Reactions, Mechanisms and Structure, John Wiley

2. P. S. Kalsi. Stereochemistry, Conformation and Mechanism, New Age International

3. Peter Sykes, A guide book to mechanism in Organic chemistry, Orient-Longmans

4. S. M. Mukherji and S. P. Singh, Reaction Mechanism in Organic Chemistry, Macmillan

5. F. A. Carey and R. J Sundberg, Advanced Organic Chemistry, Part A and B, Plenum

6. P. S. Kalsi., Organic Reactions and their Mechanisms, New Age International

MCH-201: INORGANIC CHEMISTRY- II Syllabus M.Sc.(CHEMISTRY) 2nd-II Sem Syllabus for DAVV Indore Affiliated Institutions

DEVI AHILYA VISHWAVIDYALAYA, DAVV INDORE Syllabus

M.Sc. (CHEMISTRY) Second-2nd- II Semester Curriculum/ Syllabus

MCH-201: INORGANIC CHEMISTRY- II Syllabus

Unit-I :Electronic Spectra and Magnetic Properties of Transition Metal Complexes :

Spectroscopic ground states, correlation. Orgel and Tanabe-Sugano diagrams for transition metal complexes (d1-d9 states), calculations of 10Dq, B and β parameters, charge transfer spectra, anomalous magnetic moments, Orbital contribution to magnetic moment, magnetic exchange coupling and spin crossover.

Unit-II : Metal π-Complexes

Metal carbonyl, structure and bonding, vibrational spectra of metal carbonyls for bonding and structural elucidation, important reactions of metal carbonyls; preparation, bonding structure and important reaction of transition metal nitrosyl, dinitrogen and dioxgen complexes; tertiary phosphine as ligand.

Unit-III : Boranes

Classification, preparation, reactivity, bonding and topology of Boranes, carboranes metalloboranes and metallocarbonaes.

Unit-IV : 

Metal Clusters, Chains and Fullerenes Compounds with metal-metal multiple bonds. Isopoly and heteropoly acids and their salts. Fullerenes

Books Suggested :

1. Advanced Inorganic Chemistry, F.A. Cotton and Wilkinson, John Wiley.

2. Inorganic Chemistry, J.E. Huhey, Harpes & Row.

3. Chemistry of the Elements. N.N. Greenwood and A. Earnshow, Pergamon.

4. Inorganic Electronic Spectroscopy, A.B.P. Lever, Elsevier.

5. Magnetiochemistry, R.1. Carlin, Springer Verlag.

6. Comprehensive Coordiantion Chemistry eds., G. Wilkinson, R.D. Gillars and J.A. Mc Cleverty,Pergamon.

MCH-105 (b) BIOLOGY FOR CHEMISTS Syllabus M.Sc. (CHEMISTRY) -1st-I Sem. Syllabus for DAVV Indore Affiliated Institutions

DEVI AHILYA VISHWAVIDYALAYA, DAVV INDORE Syllabus

M.Sc. (CHEMISTRY) First-1st-I Semester Curriculum/ Syllabus

 MCH-105 (b) BIOLOGY FOR CHEMISTS Syllabus
(For students without Biology in B.Sc.)

Unit-I: Cell structure and functions

Structure of prokaryotic and eukaryotic cells, intercellular organelles and their function comparison of plant and animal cells. Overview of metabolic processes -catabolism and  anabolism. ATP – the biological energy currency. Origin of life –unique properties of carbon.
Chemical evolution and rise of living systems.

Unit-II : Carbohydrates

Structure and function of important derivatives of monosaccharides like glycosides deoxy sugers, myoinositol, amino sugers. N-acetylmuramic acid. Sialic acid. Structural polysaccharide: Cellulose and chitin, Storage polysaccharide: Starch and glycogen. Structural and biological functions of glucosaminoglycans or mucopolysaccharides. Carbohydrates of glycoprotein and glycolipids. Role of sugars in biological recognition. Carbohydrate metabolism-Kreb’s cycle, glycolysis, glycogenesis and glycogenolysis, gluconeogenosis, pentose phosphate pathway.

Unit-III: Lipids

Fatty acids, essential fatty acids, structure and function of triacylglycerols,  glycerophospholipids, sphingolipids, Lippoproteins: Composition and function, role in atherosclerosis. Properties of lipids aggregates-micelles, bilayers, liposomes and their possible biological functions. Lipid metabolism-Beta-oxidation of fatty acids.

Unit-IV : Amino acids, Proteins and nucleic acid

Chemical and enzymatic hydrolysis of proteins to peptides, amino acid sequencing. Secondary
structure of proteins, α-helix ,-sheets. Super secondary structure, triple helix structure of collagen. Tertiary structure of protein-folding and domain structure. Quaternary structure. Amino acid metabolism-degradation and biosynthesis of amino acids, sequence  determination: chemical/enzymetic/mass spectral, recemization/detection. Chemistry of oxytocin and trytophan releasing hormone (TRH).
Chemical and enzymatic hydrolysis of nucleic acids. Structure of ribonucleic acids (RNA) and
deoxyribonucleic acids (DNA) double helix model of DNA and forces responsible for holding it. The chemical basis for heredity, an overview of replication of DNA, transcription, translation and genetic code. Chemical synthesis of mono and trinucleoside.

Books suggested:

1. Principles of Biochemistry, A.L. Lehninger, Worth Publishers.
2. Biochemistry, L. Stryer, W.H. Freeman.
3. Biochemistry, J.David Rwan, Nell Patterson.
4. Outlines of Biochemistry, E.E. Conn and P.K. Sumpf, John Wiley.

MCH-105 (a) : MATHEMATICS FOR CHEMISTS Syllabus M.Sc. (CHEMISTRY) -1st-I Sem. Syllabus for DAVV Indore Affiliated Institutions

DEVI AHILYA VISHWAVIDYALAYA, DAVV INDORE Syllabus

M.Sc. (CHEMISTRY) First-1st-I Semester Curriculum/ Syllabus

 MCH-105 (a) : MATHEMATICS FOR CHEMISTS Syllabus 
 (For students without Mathematics in B.Sc.) 

 Unit-I : Vectors

Vectors, dot, cross and triple products etc. gradient, divergence and curl, Vector Calculus. Differential Calculus Functions, continuity and differentiability, rules for differentiation, applications of differential calculus including maxima and minima (examples related to maximally populated rotational energy levels, Bohr's radius and most probable velocity from Maxwell's distribution etc.).

Unit-II : Integral calculus

Basic rules for integration, integration by parts, partial fractions and substitution. Reduction formulae, applications of integral calculus. Functions of several variables, partial differentiation, co-ordinate transformations (e.g. Cartesian to spherical polar).

Unit-III : Elementary Differential equations

First-order and first degree differential equations, homogenous, exact and linear equations. Applications to chemical kinetics, secular equilibria, quantum chemistry etc. second order differential equation and their solutions.

Unit-IV: Permutations and Combinations

Permutations and combinations, probability and probability theorems average, variance root
means square deviation examples from the kinetic theory of gases etc., fitting (including least
squares fit etc with a general polynomial fit.

Book Suggested

1. The chemistry Mathematics Book, E.Steiner, Oxford University Press.
2. Mathematics for chemistry, Doggett and Suiclific, Logman.
3. Mathematical for Physical chemistry : F. Daniels, Mc. Graw Hill.
4. Chemical Mathematics D.M. Hirst, Longman.
5. Applied Mathematics for Physical Chemistery, J.R. Barante, Prenice Hall.
6. Basic Mathematics for Chemists, Tebbutt, Wiley.

MCH-107: PRACTICAL Syllabus M.Sc. (CHEMISTRY) -1st-I Sem. Syllabus for DAVV Indore Affiliated Institutions

DEVI AHILYA VISHWAVIDYALAYA, DAVV INDORE Syllabus

M.Sc. (CHEMISTRY) First-1st-I Semester Curriculum/ Syllabus

MCH-107: PRACTICAL Syllabus

Chromatography Separation of cations and anions by Paper Chromatography.

Preparations

Preparation of selected inorganic compounds and their studies by I.R. electronic spectra, Mossbauer, E.S.R. and magnetic susceptibility measurements.

Qualitative Analysis

Separation, purification and identification of compounds of binary mixture (one liquid and one solid) using TLC and columns chromatography, chemical tests. IR spectra to be used for functional group identification.

Organic Synthesis

Acetylation : Acetylation of cholesterol and sepration of cholesteryl acetate by column chromatography. Oxidation : Adipic acid by chromic acid oxidation of cyclothexaneol Grignard reaction : Synthesis of triphenylmethanol from benzoic acid The Products may be Characterized by Spectral Techniques.
Drug Analysis

Physical Chemistry

Error Analysis and Statistical Data Analysis
Errors, types of errors, minimization of errors distribution curves precision, accuracy and combination; statistical treatment for erro analysis, student 't test, null hypothesis, rejection burette, piette and standard flask. Adsorption To study surface tension-connectration relationship for solutions (Gibbs equation). Phase Equilibria
i. Determination of congruent composition and temperatur5e of a binary system (e.g. diphenylamine-benzophenone system).
ii. Determination of glass transition temperature of given salt (e.g., CaCl2) conductometrically.
iii. To construct the phase diagram for three component system (e.g. chloroform-acetic acidwater).

Chemical Kinetics

i. Determination of the effect of (a) Change of temperature (b) Charge of concentration of reactant and catalyst and (c) Ionic strength of the media on the velocity constnat of hydrolysis of an ester/ionic reaction.
ii. Determination of the velocity constant of hydrolysis of an ester/ionic reaction in micellar media.
iii. Determination of the velocity constant for the oxidation of iodide ions by hydrogen peroxide study the kinetics as an iodine clock reactions.
iv. Flowing clock reactions (Ref : Experimetns in Physical Chemistry by Showmaker)
v. Determination of the primary salt effect on the kinetics of ionic reaction and testing of the Bronsted relationship (iodide ion is oxidised by persulphate ion).
vi. Oscillatory reaction.

Solution

Determination of molecular weight of non-volatile and electrolyte/electrolyte by cryoscopic method and to determine the activity coefficie nt of an electrolyte.
Determination of the degree of dissociation of weak electrolyte and to study the deviation from ideal behaviour that occures with a strong electrolyte.

Books Suggested

1. Vogel's Textbook of Quantitative Analysis, revised, J. Bassett, R.C. Denney, G.H. Jeffery and J. Mendham, ELBS.
2. Synthesis and Characterization of Inorganic Compounds, W.L. Jolly. Prentice Hall.
3. Experiments and Techniques in Organic Chemistry, D.P. Pasto, C. Johnson and M. Miller, Prentice Hall.
4. Macroscale and Microscale Organic Experiments, K.L. Williamson, D.C. Health.
5. Systematic Qualitative Organic Analysis, H. Middleton, Adward Arnold.
6. Handbook of Organic Analysis-qualitative and Quantitative. H. Clark, Adward Arnold.
7. Vogel's Textbook of Practical Organic Chemistry, A.R. Tatchell, John Wiley.
8. Practical Physical Chemistry, A.M. James and F.E. Prichard, Longman.
9. Findley's Practical Physical chemistry, B.P. Levitt, Longman.
10. Experimental Physical Chemistry, R.C. Das and B. Behera, Tata McGraw Hill.

MCH-104: Group Theory & Vibrational Spectroscopy Syllabus M.Sc. (CHEMISTRY) -1st-I Sem. Syllabus for DAVV Indore Affiliated Institutions

DEVI AHILYA VISHWAVIDYALAYA, DAVV INDORE Syllabus

M.Sc. (CHEMISTRY) First-1st-I Semester Curriculum/ Syllabus

 MCH-104: Group Theory & Vibrational Spectroscopy Syllabus

Unit-I : Symmetry and Group theory in Chemistry

Symmetry elements and symmetry operation, definition of group, subgroup. Conjugacy relation and classes. Point symmetry group. Schonfilies symbols, representations of groups by matrices (representation for the Cn, Cnv, etc, group to be worked out explicitly). Character of a
representation. The great orthogonality theorem (without proof) and its importance. Character tables and their use; spectroscopy. Derivation of character table for C2v and C3v point group Symmetry aspects of molecular vibrations of H2O molecule.

Unit-II : Microwave Spectroscopy

Classification of molecules, rigid rotor model, effect of isotopic substitution on the transition
frequencies, intensities, non-rigid rotor. Stark effect, nuclear and electron spin interaction and
effect of external field. Applications.

Unit-III : Vibrational Spectroscopy

Infrared-Spectroscopy
Review of lineear harmonic oscillator, vibrational energies of diatomic molecules, zero point energy, force constant and bond strengths; anharmonicity, Morse potential energy diagram, vibration-rotation spectroscopy. P.Q.R. branches, Breakdown of Oppenheimer approximation; vibrations of polyatomic molecules. Selection rules, normal modes of vibration, group frequencies, overtones, hot bands, factors affecting the band positions and intercities, far IR region, metal ligand vibrations, normal co-ordinate analysis.

Raman Spectroscopy

Classical and quantum theories of Raman effect. Pure rotational, vibrational and vibrational rotational Raman spectra, selection rules, mutual exclusion principle, Resonance Raman spectroscopy, coherent anti stokes Raman spectroscopy (CARS).

Unit-IV : Vibrational Spectroscopy

Symmetry, shapes and molecular vibrations of AB2, AB3, AB4, AB5 and AB6,

Books suggested

1. Modern Spectroscopy, J.M. Hollas, John Viley.
2. Applied Electron Spectroscopy for chemical analysis d. H. Windawi and F.L. Ho, Wiley Interscience.
3. NMR, NQR, EPr and Mossbauer Spectroscopy in Inorganic Chemistry, R.V. Parish, Ellis Harwood.
4. Physical Methods in Chemistry, R.S. Drago, Saunders College.
5. Chemical Applications of Group Theory, F.A. Cotton.
6. Introduction to Molecular Spectroscopy, G.M. Barrow, Mc Graw Hill.
7. Basic Principles of Spectroscopy, R. Chang, Mc Graw Hill.
8. Theory and Application of UV Spectroscopy, H.H. Jaffe and M. Orchin, IBH-Oxford.
9. Introduction to Photoelectron Spectroscopy, P.K. Ghosh, John Wiley.
10. Introduction to Magnetic Resonance. A Carrington and A.D. Maclachalan, harper & Row.