MCH-406 Chemistry of Natural Products Syllabus M.Sc.(CHEMISTRY) 4th-IV Sem Syllabus for DAVV Indore Affiliated Institutions

DEVI AHILYA VISHWAVIDYALAYA, DAVV INDORE Syllabus

M.Sc. (CHEMISTRY) Fourth-4th-IV Semester Curriculum/ Syllabus

MCH-406: Chemistry of Natural Products Syllabus

Unit – I : Terpenoids

Structure determination, stereochemistry, biosynthesis and synthesis of some common terpenopids Citral, α-Terpeneol, Farnesol, Zingiberence, Santonin, Phytol and Abietic acid.

Unit –II : Alkaloids

Structure, stereochemistry, synthesis and biosynthesis of some common alkaloids Ephedrine, Nicotine, Atropine, (+) Conin ,Quinine and Morphine.

Unit –III : 

[a] Steroids: 

Occurrence, nomenclature, basic skeleton, Diel's hydrocarbon and stereochemistry, Isolation, Structure determination and synthesis of: Cholesterol, Bile acids. Harmons: Androsterone, Testosterone, Ostrone, Progesterone, Aldosterone, Biosynthesis of Steroids.

[B] Prostaglandis

Occurrence, nomenclature, classification, biogenesis and physiological effects.

Synthesis of PGE2 and PGF2a.

Unit -IV 

[A] Plant Pigments

Occurrence, nomenclature and general methods of structure determination. Isolation and synthesis of Apigenin, Luteolin Quercetin, Myrcetin, Vitexin, Diadzein, Aureusin, Cyanidin, Hirsutidin, Biosynthesis of flavonoids: Acetate pathway and Shikimic acid pathway. Prophyrins:

Structure and synthesis of Haemoglobin and Chlorophyll.

[B] Pyrethroids and Rotenones

Synthesis and reactions of Pyrethroids and Rotenones. (For structure elucidation, emphasis is to be placed on the use of spectral parameters wherever possible).

Suggested Books:

1. Organic Chemistry : Vol. 1 and 2, I. L. Finar, ELBS

2. Organic Chemistry of Natural Products Vol. I and Vol. II, Gurdeep R. Chatwal, Himalaya Publishing House

3. Stereoselective Synthesis: A Practical Approach, M. Norgradi, VCH.

4. Rodd's Chemistry of Carbon Compounds, Ed. S. Coffey, Elsevier.

5.Introduction to Flavonoids, B.A. Bohm. Harwood Academic Publishers.

6. New Trends in Natural Product chemistry, Ataaur Rahman and M.L. Choudhary,

Harwood Academic Publishers.

7. Insecticides of Natural Origin, Sukh Dev, Harwood Academic Publishers.